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单独使用XEN45的短期结果与在开放角度的玻璃眼患者中使用XEN45与发酵化相结合的短期结果:一项回顾性研究
Vittorio Pirani1, Francesco Virgili1, Vincenzo Ramovecchi1
1ASUR-Area Vasta 3, Ospedale di San Severino Marche, Via Del Glorioso, 8, 62027 San Severino Marche, Italy.
Journal of clinical medicine
|January 11, 2024
概括
在XEN45植入物有效降低眼内压力 (IOP) 和减少药物需求在开角青光眼患者. 单独使用XEN45相比,XEN45与发泡乳化相结合,IOP的减少略大,特别是在手术后的最初一个月.
科学领域:
- 眼科医生 眼科 眼科
- 手术创新 在外科创新.
- 视光眼管理 视光眼管理
背景情况:
- 植入XEN45是一种广泛使用的设备,用于最少侵入性玻璃眼外科手术.
- 开角青光眼的管理通常需要干预措施来降低眼内压力 (IOP).
研究的目的:
- 评估XEN45植入物在减少IOP和药物依赖方面的有效性.
- 为了比较XEN45单独植入与与化相结合的结果.
主要方法:
- 在2015年6月至2021年3月期间,对677个患有开角青光眼的眼睛进行了XEN45植入 (单独或与化) 的回顾性研究.
- 主要终点:从基线到手术后6个月内心压力的平均变化.
- 二次评估:眼部低血压药物的数量变化.
主要成果:
- 在两个组中都观察到显著的内血压降低:XEN单独 (28.7至13.5 mmHg) 和XEN+Phaco (25.4至13.5 mmHg) 在6个月后 (p < 0.0001).
- 平均眼部低血压药物显著下降,从3.3降至0.2 (XEN单独) 和3.1降至0.2 (XEN+Phaco) (p < 0.0001).
- 在33.7%的眼睛中,需要注射针. 在第一个月,XEN单独组的IOP降低幅度略高.
结论:
- 植入XEN45是有效的显著降低IOP和减少对青光眼药物的需要.
- 虽然这两种手术方法都带来了巨大的好处,但XEN45单独可能在早期IOP控制中提供了轻微的优势.
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