心率变化和认知:长度研究的叙述系统审查
Paola Nicolini1, Gabriella Malfatto2, Tiziano Lucchi1
1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Geriatric Unit, Internal Medicine Department, 20122 Milan, Italy.
这一系统性审查发现,更高的心率变化 (HRV),反映了副交感神经系统的活动,预测了未来更好的认知能力,特别是执行功能. 这些发现表明HRV可能作为认知健康的生物标志物.
科学领域:
- 神经科学是一个神经科学.
- 自主生理学 自主生理学
- 认知科学 认知科学
背景情况:
- 心率变化 (HRV) 评估自主功能,并在横截面研究中与认知有关.
- HRV与认知之间的纵向关联对于预测未来的认知健康和理解因果关系至关重要.
- 没有先前的系统性审查已经综合了纵向HRV认知研究.
研究的目的:
- 系统地审查研究心率变化 (HRV) 与认知功能之间的关联的纵向研究.
- 综合当前关于HRV对认知能力下降或随着时间的推移而维持的预测价值的证据.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在Embase,PsycINFO和PubMed数据库中搜索到2023年6月.
- 包括12项纵向研究,涉及24,390名成年参与者;使用纽卡斯尔-太华尺度评估偏差风险.
主要成果:
- 所有包括的研究都报告了HRV与认知之间的纵向关联.
- 较高的副交感神经系统 (PNS) 活动始终与更好的认知表现有关.
- 较高的PNS活动预测了更好的执行功能;与记忆和语言的关联不太一致.
结论:
- HRV显示出作为预测未来认知功能的生物标志物的潜力.
- HRV可能代表认知增强的治疗目标.
- 需要通过强大的同情测量和元分析进行进一步的研究来确认.
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