在慢性功能衰竭患者中对SYNTAX评分II 2020的外部验证
Mengyao Li1,2, Xu Liu2, Mao Jiang2
1Department of Cardiology, Dongguan Cardiovascular Research Institute, Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan, China.
概括
SYNTAX II 2020 (SSII-2020) 评分有效预测PCI接受的复杂冠状动脉疾病和慢性功能衰竭患者的长期死亡率. 这一分数改善了风险分层,以改善临床决策.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 干预心脏病学 干预心脏病学
背景情况:
- SYNTAX评分II 2020 (SSII-2020) 是复杂冠状动脉疾病 (CAD) 的一个工具.
- 关于SSII-2020在经皮冠状动脉干预 (PCI) 接受CAD和慢性功能不全 (CRI) 患者的长期预测价值的研究有限.
研究的目的:
- 评估SSII-2020的预后能力,以预测PCI接受的高风险CAD和CRI患者的长期全因死亡率 (ACM).
主要方法:
- 对1156名患有CRI和复杂CAD (左主或三血管) 的患者进行了回顾性队列研究.
- 根据预测ACM的最佳门,患者被分为低,中等和高SSII-2020组.
- 使用X-tile软件来确定最佳的SSII-2020值.
主要成果:
- 在6.3年的中位随访期内,ACM率为10% (低),17% (中等) 和28% (高SSII-2020组) (p < 0.001).
- 高SSII-2020分数显著增加了ACM风险 (HR 3.289,p < 0.001与低;HR 1.757,p = 0.005与中等).
- SSII-2020显示出与原来的SYNTAX评分 (SSII) 相比的增量值,用于预测7年ACM (C指数0.662与0.534,p = 0.007).
结论:
- SSII-2020显著提高了在接受PCI的复杂CAD和CRI患者中长期ACM的预测.
- 2020年SSII促进了风险分层的改善,从而为这一患者群体带来更好的临床效用和决策.
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