在循环人体体测量过程中,运动系统血压反应与正常压力个体的未来高血压有关
Anna Carlén1, Thomas Lindow2,3, Nicholas Cauwenberghs4
1Department of Clinical Physiology in Linköping, and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping S-581 83, Sweden.
European journal of preventive cardiology
|January 11, 2024
概括
在循环人体工程学中,运动系统血压 (SBP) 反应预测了 normotensive 个体的未来高血压 (HTN). 高峰运动SBP超过参考值和更的SBP到工作速度斜坡与增加的HTN风险有关.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 预防医学 预防医学
背景情况:
- 高血压 (HTN) 是一个主要的心血管风险因素.
- 预测未来HTN在normotensive个体对于预防策略至关重要.
- 在心肺检测期间练习血压反应可以提供预后见解.
研究的目的:
- 调查运动压缩血压 (SBP) 反应与在接受循环人体体力学的正常血压个体中未来高血压 (HTN) 的发展之间的关联.
- 为了评估峰值运动SBP相对于既定参考值和运动期间SBP增加的斜率在预测事件HTN时的意义.
- 评估运动能力对运动SBP反应和未来HTN风险之间的关系的影响.
主要方法:
- 纵向队列研究分析了14428个与瑞典国家注册表相关的运动测试.
- 包括3895名没有先前心血管疾病或HTN的正常压力个体,接受最大循环人体测试.
- 测量了峰值运动SBP (SBPpeak),并将其与正常的上限 (ULN) 相比较. 计算了三个SBP到工作速率斜率 (SBP/W-斜率),考虑到不同的休息SBP参考和运动能力.
主要成果:
- 在7.5年的中位数随访期间,22%的参与者患有HTN.
- 较高的SBP峰值和超过ULN的SBP峰值与发生HTN的风险增加显著相关.
- 所有计算的SBP/W-slopes都显示出与事件HTN的积极关联,后背到顶部的SBP/W-slope显示出显著的关联.
结论:
- 夸张的运动SBP反应,定义为SBP峰值超过参考上限 (ULN) 和高SBP/W斜率,是正常压力个体未来高血压的重要预测因素.
- 这些运动SBP响应指标,特别是在考虑运动能力时,应纳入循环人体力学结果的临床评估中.
- 识别异常运动SBP反应的个体可以帮助早期风险分层和针对高血压的有针对性的预防干预措施.
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