药剂师干预对免疫接种的影响:系统性审查和元分析
Mohamad Hafiz Abd Rahim1, Siti Hajar Mahamad Dom1, Mohd Shah Rezan Hamzah1
1Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Puncak Alam Campus, Selangor Branch, Bandar Puncak Alam, Malaysia.
药剂师显著提高了公众疫苗接种率,高达51%,他们的宣传使免疫接种频率翻了一番. 这凸显了药剂师在公共卫生倡议和改善疫苗接种方面的关键作用.
科学领域:
- 公共卫生 公共卫生
- 制药科学 制药科学
- 流行病学 流行病学
背景情况:
- 免疫服务的不足利用是一个重大的公共卫生挑战.
- 药剂师越来越多地参与免疫,作为促进者和免疫剂.
- 需要关于药剂师干预措施对接种疫苗和患者结果的影响的强有力的证据.
研究的目的:
- 评估药剂师干预对公共疫苗接种率的影响.
- 综合来自随机对照试验和药剂师主导的疫苗接种倡议的非随机研究的证据.
主要方法:
- 在SCOPUS,PubMed和Web of Science进行了系统的文献搜索,直到2023年4月.
- 包括的研究包括非随机对照试验和随机对照试验与对照组.
- 进行了数据提取,偏差风险评估和随机效应模型元分析.
主要成果:
- 分析包括4个RCT和15个非RCT,涵盖流感,肺炎球菌,黄疹疫苗和破伤风-白-百日咳疫苗.
- 与常规护理相比,药剂师的干预改善了整体免疫接种率51% (RR 1.51).
- 当药剂师作为倡导者时,免疫接种频率翻了一番 (RR 2.09).
结论:
- 药剂师的参与显著提高了公共疫苗接种率,尽管药剂师免疫剂的具体证据是不同的.
- 药剂师在社区和医院环境中都在免疫计划中发挥着重要的领导和宣传作用.
- 进一步的研究应该调查药剂师参与程度及其对免疫接种的影响.
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