在治疗良性食道狭窄时,食道扩张的频率更高是否更有效? 这是一项回顾性多中心研究
Christiana Graf1, Monika Reden1, Tobias Blasberg2
1Department of Internal Medicine I, Hospital of the Goethe University Frankfurt, Frankfurt am Main, Germany.
Endoscopy international open
|January 11, 2024
概括
高频内镜扩张 (ED) 对大多数良性食道收缩更有效,导致更快的症状缓解和更大的直径. 然而,放射性狭窄受益于较少的ED会话.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 食道疾病 食道疾病
背景情况:
- 有限的证据表明,在良性食道狭窄症中,内镜治疗的最佳时间是有限的.
- 目前的建议缺乏关于内镜扩张 (ED) 疗程间隔的具体指导.
研究的目的:
- 评估ED疗程之间的时间间隔对内镜和临床结果的影响.
- 为了确定良性食道狭窄的最佳频率的布吉尼亚.
主要方法:
- 在德国两个中心对238名患有良性食道狭窄症的患者进行了回顾性分析,这些患者接受了内镜治疗.
- 高频 (中心1) 与低频 (中心2) 的ED疗程的比较.
- 主要终点:ED会话数量到缺食自由;次要终点:达到15毫米直径和临床症状自由.
主要成果:
- 在大多数患者中,高频ED在显著更早的时间内实现了临床反应.
- 接受高频率ED治疗的患者在扩张后达到更大的直径.
- 放射性后收缩显示了较低频率ED的更好的结果.
结论:
- 对于大多数良性食道收缩,高频内镜清洁疗法似乎更有效.
- 较低频率的ED对放射性食道收缩患者有益.
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