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在挪威疫苗推出期间追踪SARS-CoV-2的适应性进化

Ignacio Garcia, Yunsung Lee1, Ola Brynildsrud2

  • 1Centre for Fertility and Health, Norwegian Institute of Public Health, 0213 Oslo, Norway.

Virus evolution
|January 11, 2024
PubMed
概括

接种COVID-19疫苗并没有显著推动SARS-CoV-2的免疫逃生突变. 相反,新的高适应性突变超过其他突变的克隆干扰解释了在疫苗接种期间观察到的突变模式.

关键词:
在 COVID-19 疫情中,突变是发生在突变中的突变.人类的基因组学.接种疫苗 接种疫苗

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A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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