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Updated: Jul 5, 2025

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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同进化信息捕获了催化功能,并揭示了合成酶的不同作用,域间连接

Charisse M Nartey1, Hyun Jo Koo2, Caroline Laurendon3

  • 1Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas 75080, United States.

Biochemistry
|January 11, 2024
PubMed
概括

了解蛋白质多样性需要绘制序列功能景观. 这项研究揭示了突变如何影响烟草5-epi-aristolochene synthase (TEAS) 和premnaspirodiene synthase (HPS) 酶的产品特异性,突出了它们进化强度的关键差异.

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