疼痛预测从物质使用治疗中断
Hugh Farrior1,2, Scott Teitelbaum1, Ben Phalin1
1Department of Psychiatry, University of Florida, Gainesville, Florida.
Journal of studies on alcohol and drugs
|January 11, 2024
概括
药物使用障碍 (SUD) 治疗开始时的身体疼痛增加了学率. 将疼痛管理纳入SUD治疗对于改善患者的治疗结果和减少早期治疗停止至关重要.
科学领域:
- 成 药物 药物 药物 药物
- 疼痛管理 疼痛管理
- 心理健康 心理健康
背景情况:
- 药物使用障碍 (SUD) 是一种复杂的疾病,通常与身体疼痛同时发生.
- 对SUDs的住院治疗中高的退学率代表了成护理的重大挑战.
- 疼痛对SUD群体的治疗坚持和结果的影响需要进一步研究.
研究的目的:
- 检查治疗开始时体验到的身体疼痛与随后从住宅SUD治疗中退出的关联.
- 调查疼痛强度和认可是否预测治疗中断.
- 在阿片类药物使用障碍 (OUD) 患者中探索这些影响的潜在恶化.
主要方法:
- 分析了接受住院SUD治疗的1,095个人的队列.
- 关于疼痛认可和强度的数据是在入院后24小时内收集的.
- 使用后勤回归模型来评估疼痛和治疗中断之间的关系,控制共变量和OUD状态.
主要成果:
- 疼痛认可与更高的治疗中断频率显著相关 (OR = 1.49,p = .04).
- 增加的疼痛强度也预测了更高的学率 (OR = 1.13,p < .01).
- 在阿片类药物使用障碍状态和疼痛对中断的影响之间没有发现显著的相互作用.
结论:
- 治疗开始时的身体疼痛是住宅SUD治疗中早期学的重要预测因素.
- 将疼痛评估和管理整合到SUD治疗方案中,对于改善疼痛保留和治疗结果至关重要.
- 这些发现强调了解决疼痛的关键作用,作为综合性成护理的核心组成部分.
更多相关视频
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
2.2K
08:05A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
9.8K
相关概念视频
Substance Use Disorders Affecting Sleep
168
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
168
Drug Abuse and Addiction: Pharmacological Phenomena
476
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
476
Drug Dependence
1.0K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.0K
Stress and Mental Health
157
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
157
Desensitization and Tachyphylaxis
1.7K
Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
1.7K
Analgesia and Pain Management
625
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
625
