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相关概念视频

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Enhancing Tumor Content through Tumor Macrodissection
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在老年人中治疗DLBCL的治愈意向治疗.

Alessandra Tucci1, Lorenzo Masina1, Stefano Luminari2

  • 1Hematology Unit, ASST Spedali Civili, Brescia, Italy.

Leukemia & lymphoma
|January 11, 2024
PubMed
概括

老年人评估将具有攻击性淋巴瘤的老年人分为适合,不适合和脆弱的群体. 量身定制的治疗方法,包括新药,可以改善这些异质患者群体的治疗结果.

科学领域:

  • 在瘤学瘤学.
  • 老年病的医生 老年病的医生

背景情况:

  • 老年患有侵略性淋巴瘤的患者呈现出显著的异质性.
  • 功能限制,并发症和疾病生物学影响治疗决策.

研究的目的:

  • 为老年患有侵袭性淋巴瘤的患者概述治疗策略.
  • 突出老年评估在定制治疗中的作用.

主要方法:

  • 用多维老年学评估 (GA) 将患者分为适合,不适合和脆弱的类别进行分层.
  • 基于老年人类别的治疗方法的评估,包括R-CHOP,剂量强度降低和新型向药物.

主要成果:

  • 健身患者可以耐受标准的R-CHOP,达到与年轻患者相似的结果.
  • 不适合的患者从剂量强度的降低中受益,以平衡毒性和疗效.
  • 脆弱的患者可能会受益于新型向药物的无化疗疗法.

结论:

  • 老年人的老年评估对于个性化老年人攻击性淋巴瘤治疗至关重要.
  • 新型向性药物正在改变老年患者的治疗选择,包括一线和复发/耐药设置.
关键词:
DLBCL DLBCL 是一个字母.老年人的评估.年龄较大的患者.

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