急性期的体温和急性缺血性中风后的临床结果
Satomi Mezuki1,2, Ryu Matsuo1,3,4, Fumi Irie1,3,4
1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
PloS one
|January 11, 2024
概括
经过急性缺血性中风后的早期高体温与较差的神经恢复和较差的功能结果有关. 即使排除感染患者时,这种关联仍然存在,强调温度是关键的预后因素.
科学领域:
- 神经学 神经学
- 临床医学 临床医学
- 热调节 热调节 热调节 热调节
背景情况:
- 早期的体温是中风恢复的关键因素.
- 了解温度对神经损伤和功能的影响是必不可少的.
研究的目的:
- 研究早期中风后体温与神经损伤之间的关联.
- 确定早期体温与三个月后的功能结果之间的关系.
主要方法:
- 分析了7177名急性缺血性中风患者的队列.
- 轴心温度每天监测七天,平均温度分为五分之一.
- 后勤回归分析了体温与神经改善和功能结果 (修改的兰金表) 之间的关联.
主要成果:
- 较高的体温五分位数与显著较小的神经改善相关 (趋势P<0.001).
- 三个月后功能表现不佳的风险随着温度五分位数的升高而线性增加 (趋势P<0.001).
- 即使排除了急性感染患者后,这些关联仍然很重要.
结论:
- 脑卒中后早期升高的体温是不利结果的独立预测因素.
- 温度管理可能是改善中风预后的关键目标.
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