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Updated: Jul 5, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
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Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

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UNC93B1变种是TLR7依赖的自身免疫的基础

Christine Wolf1, Ee Lyn Lim2, Mohammad Mokhtari3

  • 1Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden 01307, Germany.

Science immunology
|January 11, 2024
PubMed
概括

在UNC93B1中的遗传变异破坏了Toll-like受体7 (TLR7) 调节,导致自身免疫性疾病. 这项研究突出了UNC93B1的重点.

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