美国成年人中BMI和葡萄糖参数与抑郁症状的时间关联
Shakila Meshkat1, Yuqing Liu2, Hyejung Jung2
1Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Ontario, Canada.
Psychiatry research
|January 11, 2024
概括
较高的体重指数 (BMI) 和异常的葡萄糖水平与抑郁症状的增加有关. 这些关联,特别是抑郁症状与BMI或HbA1c之间的关联,随着时间的推移显示出时间变化,并观察到性别差异.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 肥胖,糖尿病和抑郁症的患病率不断上升,需要了解它们之间的相互联系.
- 身体健康指标与心理健康之间的关系的时间趋势对于公共卫生战略至关重要.
研究的目的:
- 调查抑郁症状,体重指数 (BMI) 和葡萄糖概况参数之间的关系的时间趋势.
- 分析这些关联如何随着时间的推移而演变,使用大型的国家数据集.
主要方法:
- 利用了来自国家健康和营养检查调查 (2005-2018) 的数据,其中有32,653名参与者.
- 使用患者健康问卷评估抑郁症状.
- 分析了BMI,胰岛素,HbA1c,禁食葡萄糖和抑郁症状之间的关联,考虑到性别差异.
主要成果:
- 抑郁症状的风险增加与更高的BMI,胰岛素,HbA1c和禁食葡萄糖水平有关.
- 超重男性患抑郁症状的几率较低,而超重/肥胖女性患抑郁症状的几率较高.
- 随着时间的推移,高BMI/葡萄糖参数和抑郁症状之间观察到一致的关联,在特定周期中有显著的时间变化.
结论:
- 高BMI和葡萄糖参数始终与更高的抑郁症状患病率有关.
- 身体和精神健康指标之间的关联的时间动态很明显.
- 调查结果提供了对人口层面的身体和心理健康问题的趋势的见解,为公共卫生干预提供了信息.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
546
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
546
Depressive Disorders: MDD and Dysthymia
136
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
136
Depression: Overview
247
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
247
Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
Depressive Disorders: Etiology
102
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
102
Obesity
505
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
505


