通过3D打印设计使用酸及其衍生物的骨架:一篇综述
Seyedeh Farnaz Darghiasi1, Ashkan Farazin2, Hanieh Sadat Ghazali3
1Department of Mechanical & Biomedical Engineering, Boise State University, Boise, ID, USA; Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), P.O. Box 16846-13114, Tehran, Iran.
Journal of the mechanical behavior of biomedical materials
|January 11, 2024
概括
组织工程利用细胞和生物材料来创造人造组织. 使用3D打印制造的3D骨架为骨修复和再生提供了先进的解决方案.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 生物技术是生物技术.
背景情况:
- 组织工程旨在使用细胞,生物材料和生物工程恢复或替换受损的组织.
- 3D骨架对于指导新骨生长和提供机械支持至关重要.
- 像陶和聚合物这样的生物相容材料通常用于脚手架制造.
研究的目的:
- 为骨组织工程支架提供3D打印技术最新进展的概述.
- 要突出3D脚手架在模仿自然骨结构和功能中的作用.
- 讨论患者特定骨架的制造.
主要方法:
- 使用生物相容材料 (陶,聚合物) 来制造脚手架.
- 采用先进的3D打印技术,精确地构建脚手架.
- 在受控的实验室条件下在支架上培养和生长细胞.
主要成果:
- 3D打印可以创建复杂的,患者特定的脚手架几何形状.
- 支架提供必要的机械支持,并指导细胞生长,用于骨再生.
- 材料选择对于脚手架的强度,生物降解性和细胞相互作用至关重要.
结论:
- 3D打印正在彻底改变骨组织工程支架的制造.
- 患者特定的支架对改善骨修复结果具有显著的承诺.
- 对材料和印刷技术的持续研究将推动骨组织工程领域的发展.
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