急性侵袭性肺部阿斯伯吉洛症:临床表现和治疗
Jannes Heylen1, Yuri Vanbiervliet1,2, Johan Maertens1,2
1Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Seminars in respiratory and critical care medicine
|January 11, 2024
概括
侵袭性肺阿斯伯吉洛症 (IPA) 呈现急性由于阿斯伯吉洛菌的真菌入侵. 诊断依赖于临床,放射学和真菌学数据,以三醇作为主要治疗方法,但死亡率仍然很高.
科学领域:
- 医学真菌学 医学真菌学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 侵入性肺性阿斯伯吉洛症 (IPA) 是肺性阿斯伯吉洛症的最急性表现,其特征是阿斯伯吉洛菌 (Aspergillus hyphae) 侵入肺组织.
- 风险因素包括长期严重的中性质疏松症和移植对宿主疾病,但IPA也会影响其他免疫受损和非免疫受损的个体.
结论:
- 早期和准确的IPA诊断对于有效的管理至关重要.
- 优化治疗策略,包括抗真菌选择和辅助疗法,对于减少IPA相关的发病率和死亡率至关重要.
更多相关视频
09:52Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
10.6K
15:01Confocal Laser Scanning Microscopy-Based Quantitative Analysis of Aspergillus fumigatus Conidia Distribution in Whole-Mount Optically Cleared Mouse Lung
Published on: September 18, 2021
3.4K
相关概念视频
Pneumonia IV: Management
331
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
331
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180
Pneumonia I: Introduction
239
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
239
Pneumonia III: Complications and Assessment
227
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
227
Acute Respiratory Failure-V
141
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
141
COPD: Pathogenesis and Clinical Features
275
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
275
