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暴露于5天干浸泡的健康女性的神经眼科变化:试点研究

Marc Kermorgant¹, Thibault Chedmail², Fanny Varenne²

¹UMR INSERM U1297, Institute of Cardiovascular and Metabolic Diseases (I2MC), Toulouse, France.

NPJ microgravity

|January 11, 2024

概括

短期暴露于微重力会导致女性的眼睛发生轻微变化,但不会导致太空飞行相关的神经眼神综合征 (SANS) 中出现的严重症状. 需要进一步的研究来了解长期影响.

科学领域:

太空医学太空医学
眼科医生眼科眼科
人类生理学人类生理学

背景情况:

微重力诱导的液体移动会导致眼睛的变化,称为太空飞行相关的神经眼睛综合征 (SANS).
由于较少的长期任务,女性宇航员的SANS数据有限.
了解女性的这些变化对于太空探索安全至关重要.

研究的目的:

在短期暴露于微重力后,研究健康女性的眼科变化.
确定这些变化是否符合SANS标准.

主要方法:

使用自动折射计的目标折射.
用Monoyer图表进行视力敏度评估.
眼睛的轴长度,眼内压力,视网膜神经纤维层厚度 (pRNFLT),黄斑厚度和状细胞复合体 (GCC) 通过光学连贯断层扫描和生物识别测量.

主要成果:

眼睛的轴长度减少了干燥浸泡后 (DI).
在特定象限增加的PRNFLT和较低的斑点厚度.
全球海湾合作委员会是DI后最薄的.
在DI5天后,在女性中发现了轻微但显著的眼科变化.

结论:

在女性中,短期的干浸水会引起微妙的眼部变化.
这些观察到的变化不符合SANS的诊断标准.
需要进一步研究微重力对女性眼睛的长期影响.

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