肥胖,体力活动和中国中老年人的认知衰退之间的关联:调解分析
Xin Xu1,2,3, Yi Xu3, Ruolin Shi4
1Operating Room, Department of Nursing, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
BMC geriatrics
|January 11, 2024
概括
强烈的体力活动部分调解了肥胖和老年人的认知衰退之间的联系,解释了不到10%的关联. 需要进一步的研究来理解认知健康中的肥胖悖论.
科学领域:
- 老年学与公共卫生
- 神经科学与衰老问题
背景情况:
- 肥胖对中年和老年人认知能力下降的影响受到争论.
- 身体活动在这种关系中的作用尚未确立.
研究的目的:
- 为了研究肥胖和认知衰退轨迹之间的关联.
- 检查体育活动在肥胖-认知联系中的调解作用.
主要方法:
- 利用了中国健康与退休长度研究 (2011-2018) 中的7392名参与者 (年龄≥45岁) 的数据.
- 评估认知功能 (情节性记忆,精神状态) 并使用基于组的轨迹建模 (GBTM) 确定认知轨迹.
- 采用多变量逻辑回归和调解分析,使用体重指数 (BMI) 作为肥胖指标.
主要成果:
- 他们发现了四种不同的认知轨迹:高稳定,中稳定,中衰退和低衰退.
- 肥胖与低认知衰退组中的可能性较低有关 (调整后OR为0.81).
- 强烈的体力活动显著介导了5.94%的肥胖和认知衰退之间的关系.
结论:
- 强烈的体力活动解释了肥胖与老年人认知能力下降之间的关系的很小比例 (<10%).
- 这些发现突出了肥胖,体力活动和认知衰老之间的复杂关系.
- 建议进行进一步的研究,以探索导致认知健康中肥胖悖论的因素.
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