在化疗的癌症患者中推进心血管保健
Muhammad Yamin1, Simon Salim, Muhammad Syahrir Azizi
1Division of Cardiology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia. muhyam511@gmail.com.
Acta medica Indonesiana
|January 12, 2024
概括
癌症治疗相关心脏功能障碍 (CTRCD) 是一种重要的化疗副作用,影响10%的患者. 早期查和风险分层对于管理心脏毒性和改善患者结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 心脏毒性或癌症治疗相关心脏功能障碍 (CTRCD) 是一种主要的化疗副作用,影响10%的患者.
- 预计CTRCD的发病率将随着心脏毒性癌症疗法的使用增加而增加.
- 癌症患者的糖尿病和高血压等并发症复杂化了CTRCD的管理和结果.
研究的目的:
- 讨论CTRCD的评估方法.
- 为癌症治疗期间管理心脏毒性提供临床实践指导.
- 探索预防CTRCD的策略.
主要方法:
- 心声学,包括左心室喷射小部分 (LVEF) 和全球纵向菌株 (GLS),是查和诊断的关键.
- 根据临床状态,心脏毒性评估可以在化疗前,期间或之后进行.
- 许多癌症治疗中心缺乏心脏毒性风险分层分数.
主要成果:
- 医生必须仔细管理化疗剂量 (继续,停止,延迟,减少) 以减轻心脏毒性.
- 在治疗前,降低心血管风险因素和提供生活方式建议至关重要.
- 需要基于证据的心脏毒性风险评分,以便更好地分层患者.
结论:
- 有效管理CTRCD需要全面的查,风险分层和个性化治疗调整.
- 将心血管保健整合到瘤学中对于改善癌症患者的生存率和生活质量至关重要.
- 进一步的研究和基于证据的指导方针的实施是必要的,以打击化疗引起的心脏毒性.
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