孕产妇的心脏病是否会影响胎儿的心脏功能?
Gulcan Okutucu1, Deniz Oluklu1, Esra Gulen Yildiz1
1Department of Obstetrics and Gynecology, Division of Perinatology, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
概括
孕产妇心脏病显著影响胎儿的心脏功能,改变心缩和心缩参数. 患有心脏病的母亲胎儿心肌功能指数 (MPI) 的升高表明心肌功能总体受损和潜在的不良周产期结果.
科学领域:
- 心脏病学 心脏病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 母亲心脏病 (MHD) 对母亲和胎儿都有风险.
- 了解MHD对胎儿心脏发育的影响对于改善产周护理至关重要.
研究的目的:
- 研究母亲心脏病对胎儿心脏功能的影响.
- 评估被诊断患有心脏病的母亲胎儿的特定心声学参数.
主要方法:
- 研究了100名孕妇 (≥34周):有40名患有MHD和60名对照.
- 使用M模式,彩色组织多普勒成像 (c-TDI) 和脉冲波多普勒评估胎儿心脏功能.
- 使用纽约心脏协会 (NYHA) 系统分类的孕产妇心脏病.
主要成果:
- 在MHD组中的胎儿显示出显著更高的三环状平面缩外流和心肌性能指数 (MPI),延长了异体度放松时间.
- 与I类相比,在患有NYHAII类的母亲的胎儿中观察到较高的MPI值.
- 通过c-TDI,胎儿三状环状峰速没有显著变化;获得性和先天性心脏病之间没有差异.
- NYHA Class II与较低的出生体重,较低的APGAR分数和增加的NICU入院率有关.
结论:
- 孕产妇心脏病导致胎儿心脏缩和放缩功能发生变化.
- 胎儿MPI升高可能表明由于母亲心脏病理学而导致的全球心肌功能受损.
- 怀孕期间的渐进性心脏病理可能会影响胎儿的心脏功能,并与不良的围产期结局有关.
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