患有COVID-19后呼吸系统疾病的患者:胸部计算机断层扫描结果和肺功能测试,与无症状参与者进行比较
Furkan Ufuk1, Ahmet Yasin Yitik1, Burak Sarilar1
1From the Department of Radiology, University of Pamukkale, Denizli, Turkey.
Journal of computer assisted tomography
|January 12, 2024
概括
与无症状患者相比,COVID-19后呼吸系统疾病患者在CT扫描和肺功能测试 (PFT) 上显示出更大的肺异常. 这些CT发现与疾病严重程度和患者病史有关.
科学领域:
- 放射学和成像学 放射学和成像学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 在COVID-19感染后持续的呼吸系统症状,称为COVID-19后呼吸系统疾病 (rPCC),影响患者的生活质量.
- 胸部计算机断层扫描 (CT) 和肺功能测试 (PFT) 对于评估肺部健康至关重要.
研究的目的:
- 评估rPCC患者的胸部CT发现,并将其与无症状参与者 (AP) 进行比较.
- 评估在rPCC患者中CT发现和PFT之间的关系.
- 为了比较rPCC患者和APs之间的定量胸部CT发现和PFT结果.
主要方法:
- 在rPCC患者中对没有增强的胸部CT和PFT进行回顾性分析 (2020年6月-2022年9月).
- 预期形成一个对照组的APs接受类似的成像和PFTs.
- 对CT图像和PFT数据进行定性,半定量和全自动定量分析.
主要成果:
- 与AP相比,rPCC患者在CT上表现出显著更大的网膜/间隙厚和对细胞异常.
- CT程度得分与住院时间,年龄和ICU入院相关. rPCC组显示出85百分点的肺体积较低.
- 细胞异常的程度与扩散能力和强迫生命能力 (FVC) 的降低相关,以及改变的FEV1/FVC比率. rPCC组的扩散能力,FVC和肺总容量较低.
结论:
- rPCC与受损的PFTs,CT上的肺异常增加,肺体积减少有关.
- 晚年,ICU入院和长时间住院是rPCC患者胸部CT异常的危险因素.
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