在接受急性高风险腹部手术的患者中,托罗宁查的影响:一项回顾性队列研究
Charlotte T B Kanstrup1,2, Kristina Johansen Svarre1,3, Maja Christine Rasmussen1,3
1Department of Surgery, Copenhagen University Hospital - North Zealand, Hillerød, Denmark.
在急性高风险腹部手术 (AHA) 后实施热素查并没有降低30天死亡率. 在广泛查之前,需要进一步研究非心脏手术 (MINS) 后心肌损伤的预防和治疗.
科学领域:
- 心脏病学 心脏病学
- 一般外科 整体外科
- 关键护理医学 关键护理医学
背景情况:
- 急性高风险腹部手术 (AHA) 具有显著的短期死亡风险.
- 在非心脏手术 (MINS) 后的心肌损伤,以升高的托洛因为标志,有助于这种死亡率.
- 无症状的MINS往往需要进行热素查以诊断.
研究的目的:
- 评估是否常规的手术后形查和个性化干预措施可以降低AHA手术后的死亡率.
- 为了探索治疗的影响,在托罗邦尼查期间.
主要方法:
- 558名接受AHA手术的患者进行了回顾性队列研究.
- 历史对照组 (2019年3月前) 与查组 (2019年3月后) 的比较.
- 在术后测量热素I,评估心肌损伤,以及个性化多学科咨询.
主要成果:
- 查组 (336名患者) 的30天死亡率为11.1%,而对照组 (176名患者) 的13.8%.
- 没有观察到30天死亡率有统计学意义的减少 (-2.7%绝对风险差异).
- 手术后90天和1年后的结果保持不变.
结论:
- 手术后的查并没有证明与AHA手术患者的死亡率降低有关.
- 在实施标准的热素查协议之前,对MINS预防和治疗的进一步研究至关重要.
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