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Updated: Jul 5, 2025

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
08:59

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

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针对性蛋白质淘汰技术的最新进展 - - 针对性治疗的新兴范式

Mansi Joshi1,2, Pranay Dey1,2, Abhijit De1,2

  • 1Molecular Functional Imaging Lab, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.

Exploration of targeted anti-tumor therapy
|January 12, 2024
PubMed
概括

有针对性的蛋白质降解 (TPD) 通过消除有害蛋白质提供了一种新的治疗策略. 像蛋白质溶解向仿真体 (PROTACs) 和TRIM-Away等技术在治疗包括癌症在内的疾病方面表现有前途.

关键词:
蛋白质的敲除过程中,蛋白质被敲除.癌症 癌症 癌症 癌症 癌症在人体内后翻译修改后的修改蛋白质溶解的目标是嵌合体.三分之一的图案-21-21

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