在将饮食干预措施应用于癌症治疗时,要考虑代谢异质性:一篇综述
1Department of General Surgery, Chong Gang General Hospital, 400016, Chongqing, China.
Heliyon
|January 12, 2024
概括
饮食干预措施通过影响新陈代谢和免疫力,在癌症治疗中表现有前途. 然而,不一致的结果强调需要解决饮食,癌症类型和个性化癌症护理治疗的异质性.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 代谢研究研究 代谢研究
背景情况:
- 饮食干预越来越多地被用于癌症治疗,提出的机制包括代谢物剥夺,激素调节和免疫系统增强.
- 临床前和临床研究表明,饮食方法的可行性,安全性和潜在的积极瘤结果.
- 然而,目前的文献中存在显著的不一致性和相互矛盾的结果.
研究的目的:
- 审查和讨论影响癌症对饮食干预反应的异质性来源.
- 为优化癌症治疗的饮食策略提供见解.
主要方法:
- 文献综述侧重于癌症中饮食干预措施的临床前和临床研究.
- 分析导致治疗反应异质性的因素.
主要成果:
- 确定了关键的异质性因素:饮食方案,起源和位置的癌症组织,代谢异质性 (空间和时间) 和组合治疗策略.
- 这些因素显著影响不同癌症类型的饮食干预措施的有效性.
结论:
- 解决异质性对于癌症治疗中成功的饮食干预至关重要.
- 个性化的饮食策略,在正确的时间为正确的患者考虑正确的饮食,对于最大限度地提高疗效和改善患者的结果至关重要.
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