性结肠炎的临床试验设计:根据韦多利祖马布第三阶段试验GEMINI 1和VISIBLE 1的后期分析解释不断变化的终点

William J Sandborn1, Bruce E Sands2, Sharif Uddin3

  • 1Division of Gastroenterology, University of California San Diego, La Jolla, CA, USA.

Crohn's & colitis 360
|January 12, 2024
PubMed
概括

梅奥总得分,包括医生全球评估 (PGA),历来用于性结肠炎 (UC) 试验. 修改后的梅奥得分,不包括PGA,符合FDA的指导方针,并且在UC临床试验中显示出对vedolizumab的可比疗效.

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