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通过自动编码器架构对单细胞测序数据进行批次校正.

Reut Danino1, Iftach Nachman2, Roded Sharan1

  • 1Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 6997801, Israel.

Bioinformatics advances
|January 12, 2024
PubMed
概括

基于自编码器的批次校正 (ABC) 是一种新的深度学习方法,可以消除单细胞测序数据中的批次效应. 它成功地整合了数据集,同时保留了生物变异,优于现有的方法.

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.