基底动脉阻塞的内血管疗法在突然发作到最大缺陷缺血事件中
Lina Zhu1,2, Wenhua Liu3, Zhizhou Hu4
1Department of Neurology Weihai Municipal Hospital, Cheeloo College of Medicine, Shandong University Weihai China.
Journal of the American Heart Association
|January 12, 2024
概括
基底动脉封闭患者突然出现最大缺陷 (SOTMD) 并没有显著影响内血管治疗的良好结果. 然而,SOTMD患者的死亡率较高,结果严重依赖于治疗时间.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 血管神经学 血管神经学
背景情况:
- 急性基底动脉封闭 (BAO) 与突然发作至最大赤字 (SOTMD) 与严重后果有关.
- 内血管治疗 (EVT) 对SOTMD患者的影响以及发病至穿刺时间的影响仍然不清楚.
研究的目的:
- 为了评估EVT在BAO SOTMD患者的有效性.
- 调查SOTMD和非SOTMDBAO患者发病到刺穿时间对结果的影响.
主要方法:
- 对潜在的BASILAR注册表数据进行回顾性分析.
- 将BAO患者的二体化划分为SOTMD和非SOTMD队列.
- 多变量后勤回归分析结果 (有利的结果,再通道化,90天死亡率).
主要成果:
- 在SOTMD和非SOTMD队列之间,有利的结局是相似的 (OR,0.88;P=0.5).
- 在SOTMD队列中,死亡率明显高 (OR,1.67;P=0.008).
- SOTMD患者的死亡率随着时间的推移而增加;非SOTMD患者的良好结果随着时间的推移显著下降.
结论:
- 对于SOTMD和非SOTMDBAO患者来说,EVT提供了类似的有利结果.
- SOTMD患者在EVT时表现出更强的时间依赖性死亡风险.
- 时间对于有利的结果至关重要,特别是在非SOTMD患者中.
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