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Updated: Jul 5, 2025

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在非小细胞肺癌中,EEBR通过NF-κB/NLRP3信号级联诱导卡斯帕-1-依赖性热

Xin Zhao1,2, Chao Chen1, Weina Han3

  • 1Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.

Journal of cellular and molecular medicine
|January 12, 2024
PubMed
概括

一种新的化合物,EEBR,有效地减少非小细胞肺癌 (NSCLC) 的扩散和转移. 通过NF-κB/NLRP3通路,EEBR通过NF-κB/NLRP3通路触发了被编程的细胞死亡 - - pyroptosis,显示了NSCLC药物开发的潜力.

关键词:
在Caspase-1中,在 EEBRR,你会看到.GSDMDMD的总体发展目标是什么在 NF-κBB 中.在NSCLCLC中,我们可以看到.热致灭 (pyroptosis) 是一种致的过程.

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