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Updated: Jul 5, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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对CHCHD2的表观遗传抑制通过减弱的Rho A激酶活性提高了单细胞解离后的存活率

Jumee Kim1, Eun-Ji Kwon1, Yun-Jeong Kim1

  • 1College of Pharmacy, Seoul National University, 1 Gwanak-ro Gwanak-gu, Seoul, 08826, Republic of Korea.

Cellular and molecular life sciences : CMLS
|January 12, 2024
PubMed
概括

人类多能干细胞 (hPSCs) 通过表观遗传沉默CHCHD2,一个线粒体蛋白质,适应实验室培养. 这种适应减少了分裂期间的细胞死亡,这对于安全的细胞疗法至关重要.

关键词:
20q11.21 年 11 月 21 日CHCHD2是指CHCHD2的两个部分.文化适应 文化适应线粒体依赖的细胞死亡.多能干细胞是多能干细胞.摇滚 摇滚 摇滚 摇滚生存特征是一种生存特征.

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