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Updated: Jul 5, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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在儿科急诊室对药物安全干预的分析

Margaret E Samuels-Kalow1, Randall Tassone1, William Manning1

  • 1Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

JAMA network open
|January 12, 2024
PubMed
概括

药物安全药物教育 (MEDS) 干预措施减少了急诊室出院的儿童的药物剂量错误. 这种简化方法提高了药物安全性,即使在积极干预停止后,也显示了持续的益处.

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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