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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

527
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
527
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Predictive Immune Modeling of Solid Tumors
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是否特定的遗传特征预测了免疫疗法的有效性:一个病例报告.

Jun Chen1, Linrong Pang1, Lianxiang He2

  • 1Cancer Chemoradiotherapy Center, The Affiliated People's Hospital of Ningbo University, Ningbo, China.

Medicine
|January 12, 2024
PubMed
概括

一名患有复发性子宫癌的患者,缺乏标准生物标志物,对PD-1抑制剂zimberelimab反应良好. 这表明PIK3CA,ErbB2和SMAD4突变可能预测宫癌的免疫治疗反应.

科学领域:

  • 在瘤学瘤学.
  • 免疫治疗是一种免疫疗法.
  • 生物标志物发现发现

背景情况:

  • 编程死亡蛋白1 (PD-1) 阻断在复发性和转移性子宫癌中显示出有效性.
  • 已确立的PD-1抑制剂生物标志物包括PD-L1表达,瘤突变负担和微卫星不稳定性.
  • 目前的案例表明,除了已建立的生物标志物之外,还有新生物标志物的潜力.

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