在患有孤立的快速眼动睡眠行为障碍的患者中 Sarcopenia
Jinseung Kim1, Ho-Joon Lee2, Dong Ah Lee3
1Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Republic of Korea.
Sleep medicine
|January 12, 2024
概括
在患有孤立的快速眼动睡眠行为障碍 (RBD) 的患者中,临时肌肉厚度 (TMT) 降低,这表明 Sarcopenia. 这一发现表明神经退行症和肉症之间存在联系,TMT对于评估睡眠障碍中的肉症有用.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 睡眠医学 睡眠医学
背景情况:
- 评估肉症对于健康的衰老,预防功能衰退和降低跌倒风险至关重要.
- 孤立的快速眼动睡眠行为障碍 (RBD) 与神经退行性疾病有关.
- 时间肌肉厚度 (TMT) 是肉症的潜在放射性标志物.
研究的目的:
- 在患有孤立RBD的患者中调查肉类.
- 评估TMT测量的实用性,以识别这种患者群体中的肉症.
主要方法:
- 一个单一的第三级医院的回顾性研究.
- 招募了28名孤立RBD患者和30名健康对照.
- 使用脑MRI (3D T1加权成像) 测量TMT,并进行ROC分析.
主要成果:
- 与对照组 (11.843 mm) 相比,在孤立的RBD患者 (10.420 mm) 中,TMT显著降低 (p=0.002).
- 在将孤立的RBD患者与对照患者区分开来时,TMT表现良好 (AUC=0.708).
- 在孤立的RBD患者中,年龄与TMT有负相关性 (r=-0.453,p=0.015).
结论:
- 降低TMT证实了RBD孤立的患者的萨尔科佩尼亚.
- 表明神经退行症和肉症之间存在关联.
- TMT是一种可行的工具,用于评估睡眠障碍患者的萨尔科佩尼亚.
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