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Updated: Jul 5, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
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低氧和内复杂基因抑制剂通过共享机制拯救复杂I突变物

Joshua D Meisel1, Maria Miranda1, Owen S Skinner1

  • 1Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Massachusetts General Hospital, Boston, MA 02114, USA.

Cell
|January 12, 2024
PubMed
概括

通过恢复酶活性来挽救线粒体电子运输链复合I缺陷的神经疾病. 这种效应在C. elegans中保持,并与辅助子单元和ubiquinone结合口袋相关.

关键词:
类植物NADH:乌比金氧降解酶NDUFA6 时间NDUFS4 其他一个复杂的电子输送链过氧症没有氧气线粒体氧气

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A Deep-sequencing-assisted, Spontaneous Suppressor Screen in the Fission Yeast Schizosaccharomyces pombe07:55

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