为什么不可挽回性要求不足以拒绝对治疗耐药抑郁症患者的精神安乐死
1Centre for Biomedical Ethics, National University of Singapore, Singapore marcusteotianleng@gmail.com.
Journal of medical ethics
|January 12, 2024
概括
耐治疗抑郁症 (TRD) 可以通过证明当前无法治愈,而不是绝对无法治愈来满足精神安乐死的标准. 这项研究主张在评估TRD和绝症不可治愈性方面平等.
科学领域:
- 精神病学是一个精神病学.
- 医学伦理 医学伦理
- 医学哲学 医学哲学
背景情况:
- 治疗耐药性抑郁症 (TRD) 是关于精神病安乐死的辩论的核心.
- 反对者将精神疾病无法治愈的不确定性作为反对安乐死的理由.
- 无法治愈的要求 (IR) 认为,无法治愈的情况是有必要的安乐死资格.
研究的目的:
- 论证TRD患者可以满足安乐死的操作不可挽回性标准.
- 挑战绝对不可挽回的概念,而不是专注于当前的医学理解.
- 在TRD和末期恶性瘤之间评估不可救治性的平等性.
主要方法:
- 在TRD.的背景下分析不可挽回性要求 (IR).
- 对未来治疗方法和目前可用的替代方案的不可挽回性进行检查.
- 从终端恶性瘤的平价论证扩展到精神病的情况.
- 使用STAR*D试验数据开发塔利关于广义治疗耐药性的论点.
主要成果:
- 根据目前的医学科学,IR对不可挽回性的要求被解释为当前,而不是绝对.
- 考虑所有可能的未来治疗的期望被认为是不合理的安乐死资格.
- 通过考虑广义治疗耐药性的运行,可以切实地将IR应用于TRD.
- 来自STAR*D试验的实证数据支持将IR应用于TRD.
结论:
- 患有TRD的患者可以满足精神病安乐死所需的不可挽回性标准.
- 在绝对和当前不可挽回性之间进行区分,在伦理评估中偏爱后者.
- 建议在TRD和末期恶性瘤之间无法治愈的运行方面平等.
相关概念视频
Electroconvulsive Therapy
41
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
41
Psychosis: Goals of Pharmacotherapy
133
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
133
Drug Therapy
45
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
45
Psychosurgery
56
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
56
Antidepressant Drugs: MAOIs and Other Agents
237
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
237
Psychosis and Antipsychotic Drugs: Overview
263
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
263


