Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

6.5K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
6.5K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

4.0K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
4.0K
Inflammatory Response01:28

Inflammatory Response

2.0K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
2.0K
Anatomy of the Intestines01:23

Anatomy of the Intestines

72.0K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.0K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Oxygen Reduction at the Water|Oil|Electrode Interface Drives Tunable Transition Metal Hydroxide Electroprecipitation.

The journal of physical chemistry letters·2026
Same author

Hydrazine oxidation on a single electrocatalytic nanoring.

The Analyst·2025
Same author

The metabolic, microbial and immunological demands of pneumococcal colonisation.

PLoS pathogens·2025
Same author

Small molecule inhibitors of the NorA multidrug efflux pump potentiate antibiotic activity by binding the outward-open conformation.

bioRxiv : the preprint server for biology·2025
Same author

Vancomycin-resistant enterococci utilise antibiotic-enriched nutrients for intestinal colonisation.

Nature communications·2025
Same author

Non-invasive in vivo sensing of bacterial implant infection using catalytically-optimised gold nanocluster-loaded liposomes for urinary readout.

Nature communications·2024
Same journal

Adenosine as a metabolic checkpoint in CD8+ T cell dysfunction.

Trends in immunology·2026
Same journal

IL-33 scripts cancer immunity.

Trends in immunology·2026
Same journal

Mitochondrial Ca<sup>2+</sup> signaling: A metabolic rheostat defining tumor and immune cell fate.

Trends in immunology·2026
Same journal

Cross-priming underlies the efficacy of antibody-drug conjugates and immunotherapy combinations.

Trends in immunology·2026
Same journal

Gut microbiome metabolites meet immunometabolism in inflammatory bowel disease.

Trends in immunology·2026
Same journal

Metabolic regulatory nodes of the inflammasome and inflammatory cell death.

Trends in immunology·2026
查看所有相关文章

相关实验视频

Updated: Jul 5, 2025

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

4.3K

微生物群如何控制系统性天生的免疫力?

Christine K I Jordan1, Thomas B Clarke2

  • 1Centre for Bacterial Resistance Biology, Department of Infectious Disease, Imperial College London, London, UK; Life Sciences Discipline, Burnet Institute, Melbourne, VIC, Australia.

Trends in immunology
|January 12, 2024
PubMed
概括
此摘要是机器生成的。

肠道微生物群影响宿主免疫力. 这项研究提出了一个框架,以了解肠道微生物如何通过解决信号传输,免疫原始化和微生物识别来调节系统性先天免疫力.

关键词:
感染的感染感染.我们的微生物群.系统性天生的免疫力

更多相关视频

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.0K
Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

13.0K

相关实验视频

Last Updated: Jul 5, 2025

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
05:27

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions

Published on: June 30, 2021

4.3K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.0K
Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
08:33

Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment

Published on: November 17, 2018

13.0K

科学领域:

  • 微生物学 微生物学
  • 免疫学 免疫学 免疫学
  • 胃肠病学 胃肠病学

背景情况:

  • 肠道微生物群显著影响哺乳动物的先天免疫力.
  • 肠道微生物控制系统组织内天生的防御机制的机制尚不清楚.

研究的目的:

  • 解决了解肠道微生物群如何调节系统性先天免疫的关键挑战.
  • 提出一个关于肠道微生物如何调节宿主防御的框架.

主要方法:

  • 这项研究是一个概念框架,并提出了未来研究的领域.
  • 专注于信号传输,免疫启动和微生物识别.

主要成果:

  • 提出解密微生物信号传输到远端组织的解决方案.
  • 提供了关于肠道微生物如何在不引起病理的情况下促进全身免疫力的见解.
  • 建议识别调节全身免疫力的特定微生物的方法.

结论:

  • 了解肠道微生物群在系统免疫中的作用需要解决信号通路,受控免疫反应和特定的微生物参与者.
  • 为未来对肠系统免疫相互作用的研究提供了基础框架.