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Updated: Jul 5, 2025

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
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Published on: May 10, 2024

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在Ras信号通路中的药物重定位中的形状多样性和蛋白质-蛋白质接口

Ahenk Zeynep Sayin1, Zeynep Abali2, Simge Senyuz2

  • 1Department of Chemical and Biological Engineering, College of Engineering, Koc University, Rumeli Feneri Yolu Sariyer, 34450, Istanbul, Turkey.

Scientific reports
|January 12, 2024
PubMed
概括

这项研究提出了一种新的方法,通过分析蛋白质-蛋白质接口来重新利用癌症中的药物. 它通过将药物结合接口与Ras信号通路中的接口相匹配来识别潜在的癌症药物,包括HIV蛋白酶抑制剂.

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