超隔膜喷气氧化和通风改善了内镜逆行胆血管细胞造影期间的氧化:一个随机控制的临床试验
Dan Su1, Wei Zhang1, Jingze Li2
1Department of Anesthesia, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
BMC anesthesiology
|January 12, 2024
概括
通过鼻喷气管进行超管喷气氧化和通风 (SJOV) 有效地减少了ERCP深度镇静期间的缺氧. 这种方法改善了镇静剂患者的氧化,与标准氧气输送相比,降低了不良事件.
科学领域:
- 麻醉学 麻醉学
- 呼吸系统医学 呼吸系统医学
- 胃肠病学 胃肠病学
背景情况:
- 低氧是深度镇静患者的常见不良事件,特别是在ERCP等手术期间的半躺姿势.
- 保持足够的氧化对于深度镇静期间的患者安全至关重要.
研究的目的:
- 评估通过Wei鼻喷气管 (WNJ) 进行的气喷气氧化和通风 (SJOV) 是否可以降低接受ERCP的深度镇静患者缺氧的发生率.
- 为了比较SJOV与标准氧化方法的疗效.
主要方法:
- 总共有171名患者被随机分为三个组:鼻气道氧气,WNJ氧气和SJOV通过WNJ.
- 主要结局是与镇静相关的不良事件的发生率,包括低氧化和亚临床呼吸抑制.
- 二次结果包括其他手术内和手术后不良事件.
主要成果:
- 与鼻气道和WNJ组相比,SJOV组的低氧化和亚临床呼吸抑制发病率明显较低 (P <0.05).
- 在SJOV组中没有发生严重的缺氧,而在其他两个组中观察到.
- 两组之间没有发现其他不良事件的显著差异.
结论:
- 通过Wei鼻喷气管进行超隔膜喷气氧化和通风 (SJOV) 是一种有效的方法,可以在半卧姿的深度镇静患者中改善ERCP期间的氧化.
- 通过降低低氧血和呼吸抑制的风险,SJOV提供了显著的安全益处.
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