在接受SSRI治疗的抑郁症女性中,辅助使用益生菌对性功能的影响:双盲随机对照试验
Nazir Hashemi-Mohammadabad1, Seyed-Abdolvahab Taghavi2, Nicky Lambert3
1Department of Psychiatry, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.
BMC psychiatry
|January 12, 2024
概括
口服益生菌可以改善女性的性功能和满意度,抑郁症治疗SSRI. 这项研究发现,在使用益生菌8周后,性功能显著改善,抑郁症状减少.
科学领域:
- 精神病学是一个精神病学.
- 胃肠病学 胃肠病学
- 妇女健康 妇女健康
背景情况:
- 抑郁症影响5%的成年人,往往导致被忽视的性功能障碍.
- 选择性色素再吸收抑制剂 (SSRI) 可以加剧性副作用.
- 改善性功能对于整体心理健康至关重要.
研究的目的:
- 评估口服益生菌对患有抑郁障碍的女性在SSRI治疗中的性功能的影响.
- 为治疗SSRI诱导的性功能障碍提供益生菌疗效的科学证据.
- 评估对抑郁症严重程度和性满意度的影响.
主要方法:
- 双盲随机临床试验,涉及112名被诊断患有抑郁症的女性.
- 组A接受了Lactofem (口服益生菌) 加上SSRI;组B仅接受了SSRI八周.
- 评估性功能 (FSFI),抑郁症严重程度 (汉密尔顿尺度) 和性满意度 (拉森尺度).
主要成果:
- 在干预后的两组中都观察到性满意度和抑郁症严重程度的统计显著改善 (P < 0.05).
- 与单独服用SSRI组相比,Lactofem加SSRI组在所有女性性功能指数 (FSFI) 领域和总得分显著改善 (P <0.05).
结论:
- 口服益生菌补充剂 (Lactofem) 可能会增强SSRI治疗抑郁症的女性的性功能和满意度.
- 益生菌显示出减轻SSRI相关性功能障碍和改善整体心理健康的潜力.
- 需要进一步的研究来证实这些发现,并探索潜在的机制.
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