在中风中COVID-19严重程度和死亡率:临床和实验室参数的相关性
Abdul Gofir1, Irawan Satriotomo2, Yossy Catarina Budi Nur Syamsah3
1Department of Neurology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/ Dr. Sardjito General Hospital, Jalan Farmako Sekip Utara, Sleman, Mlati, Yogyakarta, 55281, Indonesia. gofir@ugm.ac.id.
BMC neuroscience
|January 12, 2024
概括
卒中是一种严重的COVID-19并发症. 失去意识,运动缺陷,呼吸困难和高单细胞计数预测这些患者的死亡率. 随着多个因素的共存,风险就会增加.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 脑卒中是COVID-19的一个显著的神经并发症,与增加的发病率和死亡率有关.
- 了解COVID-19中风患者死亡率的预测因素对于临床管理至关重要.
- 这项研究调查了与该患者群体死亡率相关的临床和实验室因素.
研究的目的:
- 确定急性中风和确诊COVID-19的患者死亡率的预测因素.
- 分析临床表现,实验室参数和死亡率之间的关联.
- 为临床决策提供信息,并改善COVID-19中风患者的治疗结果.
主要方法:
- 在印度尼西亚Sardjito总医院进行了一项病例控制研究 (2020年7月至2021年8月).
- 收集和分析了72名COVID-19急性中风患者的临床和实验室数据.
- 进行了双变量和多变量分析,包括危险比率 (HR) 计算,以确定死亡率预测因素.
主要成果:
- 该研究包括72名COVID-19中风患者;大多数人患有缺血性中风和高血压.
- 死亡的重要预测因素包括意识丧失 (HR=2.68),运动缺陷 (HR=2.34),呼吸困难 (HR=81.51),和单细胞数升高 (HR=1.002).
- 观察到严重的COVID-19 (52.8%),呼吸困难 (56.9%) 和高死亡率 (58.3%).
结论:
- 患有中风的COVID-19患者的死亡率与意识丧失,运动缺陷,呼吸困扰和单细胞计数增加有显著联系.
- 多种风险因素的存在会增加死亡风险.
- 这些发现强调了监测这些因素的重要性,以改善患者的治疗结果.
相关概念视频
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