在绝经后妇女中对25 (OH) 维生素D3和四头肌强度相关性的评估:一个横截面研究
Pınar Özbudak1,1, Özlem Karataş2, Cahit Kaçar2,1
1Faculty of Medicine, Gazipaşa Public Hospital, Antalya, Turkey.
Journal of back and musculoskeletal rehabilitation
|January 13, 2024
概括
维生素D缺乏症在绝经后妇女中很常见. 这项研究发现,在这个群体中,维生素D水平和四头肌肌肉力量之间没有统计学意义上的联系.
科学领域:
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
- 肌肉骨健康 肌肉骨健康
背景情况:
- 维生素D缺乏症在绝经后妇女中很普遍,与摄入量低和年龄等因素有关.
- 缺乏症可能会加剧肌肉软弱和失衡,增加骨折风险,特别是在老年人中.
研究的目的:
- 为了研究25(OH) 维生素D3水平与绝经后妇女四头肌肌肉强度之间的关系.
主要方法:
- 双边四头肌肌的强度是通过对绝经后妇女的异动力学测试来评估的.
- 研究人员检查了肌肉强度与偏激素,维生素D,,肌,氨酸转胺酶,性酸酶和总肌激酶水平之间的相关性.
主要成果:
- 这项研究包括95名参与者,平均维生素D水平为18.24 ± 8.94 ng/ml.
- 很大一部分人缺乏 (24.1%) 或缺乏 (65.26%) 维生素D水平.
- 发现维生素D水平与偏激素 (PT) 值之间存在弱负相关性 (r=-0.271,p=0.012),与性酸酶 (ALP) 之间存在中度负相关性 (r=-0.317,p=0.002).
- 没有观察到维生素D水平与四头骨曲和延伸在60°和90°的峰值扭矩值之间的显著相关性.
结论:
- 在这个队列中,维生素D水平与四头肌肌肉强度没有统计学上显著的相关性.
- 需要进一步的研究,以建立一个更明确的共识,在维生素D和肌肉力量在绝经后妇女之间的关联.
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