在早产婴儿患有手术性死性肠球炎和相关结局的术后并发症的危险因素
P P Garg1, R Riddick1, M A Y Ansari2
1Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi, USA.
Journal of neonatal-perinatal medicine
|January 13, 2024
概括
在为死角性肠球炎 (NEC) 或自发性肠穿孔 (SIP) 接受手术的早产婴儿中,术后并发症很常见. 风险因素包括女性性别,额外的发病率和生长失败,但不包括死亡率.
科学领域:
- 新生儿手术 新生儿手术
- 儿科胃肠病学 儿科胃肠病学
- 临床风险因素分析.
背景情况:
- 结核性肠球炎 (NEC) 和自发性肠孔 (SIP) 是早产婴儿的关键手术条件.
- 手术后并发症对这些易受伤害的新生儿的影响很大.
研究的目的:
- 确定为NEC或SIP进行手术的早产婴儿中与术后并发症相关的临床风险因素.
- 为了区分单个和多个术后并发症的风险因素.
主要方法:
- 追溯队列研究的设计.
- 包括手术NEC或SIP的早产婴儿.
- 婴儿与没有术后并发症之间的临床因素的比较.
主要成果:
- 71.5%的婴儿经历了术后并发症.
- 单一并发症与较低的产前类固醇暴露和较高的结核切除率有关.
- 多重并发症与女性性别,急性损伤 (AKI) 在发病时和较差的生长参数有关.
结论:
- 有手术NEC/SIP和术后并发症的早产婴儿更有可能是女性,有并发症,并表现出生长失败.
- 产前类固醇暴露对单一并发症有保护作用,而凝肠切除术和AKI增加了风险.
- 在患有术后并发症和没有术后并发症的婴儿之间没有观察到死亡率的显著差异.
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