在新加坡遵守二次中风预防药物:单一中心研究
Pei Shieen Wong1, Kaavya Narasimhalu2, Siaw Li Tio3
1Department of Pharmacy, Singapore General Hospital, Singapore; Department of Pharmacy, National University of Singapore, Singapore.
概括
缺血性中风后的药物坚持不好,特别是对于他类药物. 了解生活状况和对药物的信仰等因素是改善二次中风预防和减少复发性中风风险的关键.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 经常性中风导致严重的残疾和死亡率.
- 对二次中风预防药物的低最佳遵守是令人担忧的.
- 有效的二次预防对中风幸存者至关重要.
研究的目的:
- 为了评估抗高血压药物,抗血小板药物和病类药物的药物坚持. 缺血性中风后.
- 为了确定与每个特定药物类别的不遵守相关的因素.
- 为改善二次中风预防提供有针对性的干预信息.
主要方法:
- 在一个单一的门诊中风后诊所进行前性队列研究.
- 药物坚持和知识通过直接询问进行评估.
- 关于药物的信念 用于评估药物感知的问卷.
- 后勤回归分析了与不遵守相关的因素.
主要成果:
- 坚持率不同:抗高血压药物 (77.9%),抗血小板药物 (80.3%) 和他类药物 (64.7%).
- 不坚持的因素包括独自生活,少服用药物和负面的药物信仰.
- 确定了每个药物类别的特定因素,包括糖尿病状况和事件发生以来的时间.
结论:
- 对于二次中风预防的整体药物坚持是次优的.
- 在研究的药物类别中,他类药物表现出最低的坚持率.
- 识别特定类别的不坚持因素可以指导定制的干预策略.
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