在患有脑静脉血栓症的患者中,与最初的内出血发生相关的因素
Suppakorn Yamutai1, Pitchayaporn Sornplaeng1, Nuttha Sanghan2
1Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, 15 Kanjanavanich Road, Hat Yai, Songkhla 90110, Thailand.
Clinical neurology and neurosurgery
|January 13, 2024
概括
内出血发生在36.63%的泰国脑静脉血栓症 (CVT) 患者中. 在CVT患者中,发作,焦点神经缺陷和上斜侧鼻血栓形成与ICH独立相关.
科学领域:
- 神经学 神经学
- 血管神经学 血管神经学
- 神经成像是一种神经成像.
背景情况:
- 内出血 (ICH) 是脑静脉血栓 (CVT) 的罕见但严重并发症.
- 有限的研究已经研究了CVT患者中与ICH相关的特定因素,特别是在亚洲人群中.
研究的目的:
- 确定与泰国诊断为CVT的患者发生ICH相关的临床,放射学和病因学因素.
- 为患有出血风险的CVT患者提供有关风险分层和管理策略的见解.
主要方法:
- 在2002年至2022年期间,对202名CVT患者进行了回顾性队列研究,这些患者于2002年至2022年入院于高等大学医院.
- 患者被分为ICH和非ICH组,并比较了基线特征,临床表现和放射性发现.
- 用多变量逻辑回归分析来确定CVT中ICH的独立预测因子.
主要成果:
- 在CVT患者中,ICH的发病率为36.63%.
- ICH与较高的焦点神经缺陷,发作,入院时的依赖性,上部斜侧鼻血栓症,表面皮层静脉血栓症和荷尔蒙使用的患病率显著相关.
- 发作 (aOR 4.537),焦点神经缺陷 (aOR 2.431),以及上部斜侧鼻血栓 (aOR 1.922) 被确定为CVT患者中ICH的独立预测因素.
结论:
- 发作,焦点神经缺陷和上斜鼻血栓症是脑静脉血栓症患者内出血的重要独立危险因素.
- 这些发现强调了识别这些临床和放射性迹象对于在CVT中早期发现和管理ICH的重要性.
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