在疫情爆发期间,儿童中和水之间的差异和相似之处
E Riche1, S Aherfi2, P Colson3
1Service d'Accueil des Urgences Pédiatriques, Hôpital Nord, AP-HM, AMU, Marseille, France.
Travel medicine and infectious disease
|January 13, 2024
概括
猿病毒 (MKPV) 很少在患有水状皮疹的儿童中被诊断出. 大多数疑似儿科MKPV病例被证实为天花病毒 (VZV),突出了诊断挑战.
科学领域:
- 儿童传染病 儿童传染病
- 病毒皮肤病学 病毒皮肤病学
- 动物传播疾病的流行病学.
背景情况:
- 2022年病毒 (MKPV) 疫情在非流行国家中出现了罕见的儿科病例.
- 区分MKPV与儿童其他皮疹引起的疾病是具有挑战性的.
- 由疹病毒 (VZV) 引起的水是一种常见的儿童疾病,具有皮疹呈现.
研究的目的:
- 调查最初怀疑感染的儿童中病毒 (MKPV) 发生率.
- 为了区分MKPV与水病毒 (VZV) 在儿科患者出现皮疹.
- 在儿科队列中评估MKPV的诊断准确性.
主要方法:
- 对怀疑MKPV感染的16岁以下儿童进行了回顾性研究.
- 在皮肤病变抽样上进行MKPV DNA和VZV DNA的PCR测试.
- 从2022年3月23日到2022年10月20日收集的数据.
主要成果:
- 怀疑MKPV的14名儿童中,没有一个MKPVDNA检测呈阳性.
- 在17% (30/168) 的儿科皮肤擦片中检测到疹病毒 (VZV) DNA.
- 七名VZV阳性儿童有非典型的皮疹,最初怀疑是MKPV.
结论:
- 在非流行地区的2022年疫情期间,儿科猿病毒 (MKPV) 病例很少见.
- 脊髓灰质炎病毒 (VZV) 感染是比MKPV更常见的儿童皮疹的原因.
- 对于MKPV在儿童中的潜在密切接触或性传播以及新型更具传染性的变种,需要保持警.
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