门系统静脉突变和子宫内生长限制:来自前性研究的调查
Shelly Czeiger1, Tal Weissbach2, Keren Zloto3
1Obstetrics and Gynecology Ultrasound Unit, Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel; Department of Obstetrics and Gynecology, Mayanei HaYeshuha Medical Center, Bnei-Brak, Israel.
American journal of obstetrics and gynecology
|January 13, 2024
概括
门系统静脉突变在胎儿生长限制中很常见,增加胎儿死亡和早产的风险. 评估胎儿门系统对于管理子宫内生长限制和改善围产期结果至关重要.
科学领域:
- 围产儿医学 围产儿医学
- 胎儿心脏病学 胎儿心脏病学
- 医疗成像医学成像
背景情况:
- 胎儿门静脉系统的先天性异常可能与不良的围产期结局有关.
- 以前的研究表明,门系统静脉突变和子宫内生长限制 (IUGR) 之间存在联系.
- 带有IUGR的胎儿中移植系统性分流的患病率需要进一步确定.
研究的目的:
- 确定门系统静脉分流在受IUGR影响的怀孕中的流行率.
- 为了比较带有和没有这些避孕套的怀孕之间的围产和新生儿结局.
主要方法:
- 一项前性,横截面研究包括基于母胎医学协会指导方针的IUGR诊断的怀孕.
- 进行了详细的异常扫描,包括使用彩色多普勒对胎儿门户系统的有针对性的评估.
- 在IUGR怀孕中与没有门系统静脉分离器之间比较了周产期结局.
主要成果:
- 在150个IUGR病例中,门系统静脉突变的患病率为9.3%.
- 这些怀孕显示出更早的IUGR诊断,分娩,更高的胎儿死亡率 (21.4%),以及更多的胎儿血管异常.
- 异常的静脉管道多普勒指数更频繁,而异常的子宫动脉多普勒指数和高血压障碍较少.
结论:
- 门系统静脉突变是IUGR胎儿的一个值得注意的发现,影响围产期的结果.
- 这些突变与明显的多普勒模式,胎儿死亡风险增加和IUGR早期呈现有关.
- 在IUGR产前检查中,建议对胎儿门系统进行超声波评估.
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