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Updated: Jul 5, 2025

Deciphering High-Resolution 3D Chromatin Organization via Capture Hi-C
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使用纳米孔和Hi-C技术对Decapterus maruadsi基因组进行染色体层次的组装和基因注释

Longyu Chen1,2, Zhixiong Zhou1,2, Zhiyin Zhou1,2

  • 1State Key Laboratory of Mariculture Breeding, College of Ocean and Earth Sciences, Xiamen University, Xiamen, 361102, China.

Scientific data
|January 13, 2024
PubMed
概括

研究人员已经开发出一个高质量的参考基因组,用于商业价值的鱼,Decapterus maruadsi. 这种基因组资源有助于对这种重要的海洋物种进行生殖质评价和保护工作.

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Genome Annotation and Assembly03:36

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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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