心上脂肪组织体积与左心房体积指数之间的关系中的性别差异
Satoshi Yamaguchi1,2, Minetaka Maeda3, Kageyuki Oba3
1Department of Diabetes, Endocrinology and Metabolism, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1247, Japan.
BMC cardiovascular disorders
|January 13, 2024
概括
副心脏脂肪组织体积 (EATV) 对左心房 (LA) 尺寸的影响在男性和女性中不同. 这项研究揭示了EATV和LA体积在患有鼻节律或心房动的患者中存在的性别特定关联.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 人们已经认识到心血管疾病的性别差异.
- 表心脂肪组织体积 (EATV) 对心血管健康的影响因性别而异.
- 根据性别,EATV对左心房 (LA) 大小的具体影响仍然不清楚.
研究的目的:
- 调查心表脂肪组织体积指数 (EATVI) 和左心房体积指数 (LAVI) 之间的性别差异.
- 在患有鼻节律 (SR) 和心房动 (AF) 的患者中探索这些关联.
主要方法:
- 在247名没有显著冠状动脉疾病或膜疾病的受试者中利用多探测器计算机断层扫描.
- 将患者分为SR (63) 和AF (184) 组.
- 采用单变量和多变量回归分析来评估EATVI-LAVI关系中的性别差异.
主要成果:
- 总的来说,在SR或AF患者中没有观察到EATVI和LAVI之间的显著相关性.
- 显著的性别差异出现了:在SR的男性中,有一个积极的EATVI-LAVI关系,而在SR的女性中,没有关联.
- 在AF患者中,在女性中发现了负的EATVI-LAVI关系,在男性中没有关联.
结论:
- 这项研究是第一个报告EATVI-LAVI协会中的性别差异的研究.
- 在SR的男性中观察到积极的关联,在AF的女性中观察到负面的关联.
- 研究结果表明,EATV可能导致心房的病因性差异.
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