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Updated: Jul 5, 2025

Flow Cytometry-based Drug Screening System for the Identification of Small Molecules That Promote Cellular Differentiation of Glioblastoma Stem Cells
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通过调节JAK/STAT3/bFGF信号通路,IFITM3促进了结质母细胞瘤干细胞介导的血管生成

Zhangsheng Xiong1,2, Xiangdong Xu1,2, Yuxuan Zhang1,2,3

  • 1Department of Neuro-oncological Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, 510060, PR China.

Cell death & disease
|January 13, 2024
PubMed
概括

干扰素诱导的跨膜蛋白3 (IFITM3) 通过激活Jak2/STAT3信号和增加bFGF分泌来促进多形质母细胞瘤 (GBM) 血管生成. 这一发现凸显了IFITM3作为GBM的潜在治疗点.

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