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Updated: Jul 5, 2025

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DiffDomain 可以识别结构重组的拓关联域

Dunming Hua1,2, Ming Gu1,2, Xiao Zhang1,2

  • 1Department of Biostatistics and Systems Biology, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, 510275, China.

Nature communications
|January 13, 2024
PubMed
概括

一种新的计算方法DiffDomain准确地识别了在3D基因组组织中重组的拓关联域 (TAD). 该工具通过使用染色体构造捕获数据,增强对健康和疾病中的基因组结构变化的分析.

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