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Updated: Jul 5, 2025

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对于hERG1通道缓慢失活至关重要的细胞内疏水性结合

Whitney A Stevens-Sostre1, Lisandra Flores-Aldama1, Daniel Bustos2

  • 1Department of Neuroscience, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Biophysical journal
|January 14, 2024
PubMed
概括

在hERG1通道中的一个关键的疏水连接点通过将PAS-cap尖端放置在电压传感器和门附近来控制缓慢的停用. 这种相互作用对于调节通道功能至关重要.

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