托克索普拉斯莫斯与怀孕年龄较小的新生儿之间的相关性
Bratislavske lekarske listy
|January 14, 2024
概括
孕妇的潜在毒素菌增加了分娩时为孕期小 (SGA) 婴儿的风险. 这项研究发现,SGA婴儿出生于患有潜毒素的母亲的风险是1.567倍.
科学领域:
- 医学研究 医学研究
- 传染性疾病 传染性疾病
- 产科 产科 产科 产科 产科
背景情况:
- 怀孕期间的Toxoplasma gondii感染可能会对怀孕结果产生负面影响.
- 对于妊娠年龄来说小 (SGA) 被定义为出生体重低于妊娠年龄的第10个百分位.
- 潜伏性毒素菌与SGA分娩之间的关联需要进一步调查.
研究的目的:
- 调查怀孕妇女的潜在毒素菌与SGA婴儿分娩之间的联系.
- 为了确定潜在的Toxoplasma gondii感染是否是SGA分娩的危险因素.
主要方法:
- 研究了一组1647名妇女,她们在预期期 (≥37周妊娠期) 交付单独婴儿.
- 通过补充定试验 (CFT) 和IgG/IgM酶相关免疫吸收试验 (ELISA) 诊断出潜毒素.
- 潜在感染标准:CFT titre ≥ 1:8,IgG ELISA指数>1.1,以及负的IgM.
主要成果:
- 在406名 (24.7%) 妇女中检测到潜在的毒素菌.
- 190 (11.5%) 的分娩导致SGA婴儿.
- 在潜伏性毒素菌和SGA分娩之间发现了统计学上显著的关联 (皮尔森基平方,p = .007).
结论:
- 孕妇患有隐性毒素菌有1.567倍更高的风险交付一个SGA婴儿到期.
- 隐性毒素菌是SGA分娩的重要危险因素.
- 这些发现强调了在孕妇群体中查毒素菌的重要性.
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